Our crops obtain fungal resistance by enhanced Nepenthesin Expression (ENE). Nepenthesin is a naturally occurring protease first identified in the pitcher secretions of plants of the Nepenthes genus, a group of carnivorous plants.
The resistance mechanism is non-cytotoxic but works through inhibition of fungal activity of phytase, an enzyme essential for releasing phosphate required for fungal growth. The result is starvation of the fungus and therefore reduced growth and toxin production. As the inhibition mechanism involves multiple interactions between the inhibitor and the enzyme, the risk of rapid development of fungal resistance is considered very low.